Chronic Pain and Brain Abnormalities by Carl Y. Saab

By Carl Y. Saab

It is simply traditional for somebody in soreness to take care of the physique half that hurts. but this ebook tells the tale of power discomfort having unwanted effects on mind functionality. The individuals, all major specialists of their respective fields of discomfort electrophysiology, mind imaging, and animal types of soreness, attempt to synthesize compelling and, in many ways, attached hypotheses with reference to pain-related adjustments within the mind. jointly, they give a contribution their medical, educational, and theoretical services in a accomplished evaluate that makes an attempt to outline the wider philosophical context of discomfort (disentangling sensical from nonsensical claims), list the adjustments recognized to occur within the brains of people with power ache and animal versions of ache, tackle the prospective factors and mechanisms underlying those alterations, and element the options and analytical tools at our disposal to "visualize" and research those adjustments.

  • Philosophical and social recommendations of discomfort; testimonials of chronic-pain patients
  • Clinical information from ache sufferers’ brains
  • Advances in noninvasive mind imaging for discomfort patients
  • Combining theoretical and empirical ways to the research of pain-related mind function
  • Manipulation of mind functionality in animal versions
  • Emerging neurotechnology ideas for discomfort diagnostics and therapeutics

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Diagnostic and Statistical Manual of Mental Disorders. 4th ed. American Psychiatric Association; 2000. 75. Schaeffer AJ, Datta NS, Fowler Jr JE, et al. Overview summary statement. Diagnosis and management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Urology. 2002;60(6 suppl):1–4. 76. Farmer MA, Chanda ML, Parks EL, Baliki MN, Apkarian AV, Schaeffer AJ. Brain functional and anatomical changes in chronic prostatitis/chronic pelvic pain syndrome. J Urol. 2011;186(1):117–124. 77. Schweinhardt P, Kuchinad A, Pukall CF, Bushnell MC.

Chapter 27: chronic nonspecific back pain. In: Olaogun MOB, ed. Guide to Pain Management in Low-Resource Settings. Seattle: International Association for the Study of PAIN; 2010. p. 207–212. 68. Schmidt-Wilcke T, Leinisch E, Ganssbauer S, et al. Affective components and intensity of pain correlate with structural differences in gray matter in chronic back pain patients. Pain. 2006;125(1-2):89–97. 69. Elbert T, Flor H, Birbaumer N, et al. Extensive reorganization of the somatosensory cortex in adult humans after nervous system injury.

CHRONIC PAIN AND BRAIN ABNORMALITIES 44 3. THALAMIC BURST FIRING IN RESPONSE TO EXPERIMENTAL PAIN STIMULI CORTICAL PAIN NETWORK Our studies of pain-related causality have demonstrated that attention to a painful stimulus leads to a consistent increase in directed functional interactions in pain-related cortical modules during both the pre-stimulus and post-stimulus periods. 51–53 Causality is a property by which the signal at one electrode exerts a causal influence upon the signal at another electrode.

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