Chlorinated Paraffins by Heidelore Fiedler (auth.), Jacob Boer (eds.)

By Heidelore Fiedler (auth.), Jacob Boer (eds.)

Chlorinated paraffins are one of many final periods of chlorinated compounds which are nonetheless being produced around the globe and utilized in excessive amounts in lots of purposes. they're fairly utilized in slicing oils within the steel undefined, but additionally as lubricants, plasticizers, flame retardants and as ingredients in adhesives, rubber, paints and sealants. This quantity covers the cutting-edge of tools for the synthesis and research of chlorinated paraffins. specialists within the box supply an outline in their world wide prevalence and usage and describe their toxicological houses. foreign rules and creation volumes are offered in addition to an instance of a hazard review learn that was once conducted in Japan. This e-book is a useful and entire resource of data for environmental scientists drawn to the incidence and toxicology of chlorinated paraffins and for experts and producers.

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Australian Government, Department of Health and Ageing, National Industrial Chemicals Notification and Assessment Scheme (NICNAS) (cited by [2]) 17. Comments submitted to the Stockholm Convention Secretariat on 7 April 2008 for POPRC SCCPs risk profile 18. K. Environment Agency (2003) Updated risk assessment of alkanes, C10–13, chloro (cited by [2]) 19. Government of Canada (1993) Canadian Environmental Protection Act. Priority Substances List supporting document. Chlorinated paraffins. Environment Canada and Health and Welfare Canada.

Fiedler Synthesis of Information Gathered SCCPs are persistent, bioaccumulative and toxic to some species, and undergo long-range transport to remote areas. Total reported annual usage of SCCPs was high in several countries, but several have had notable reductions in recent years. For example, use in Canada was approximately 3,000 tons in 2000 and 2001 [49]; in Switzerland 70 tons were used in 1994, which is likely to be reduced by 80% now (Annex E submission); and in Western Europe, usage was reduced from 13,208 tons in 1994 [13] to 4,075 tons in 1998 [7].

The EU Risk Assessment Report [8] summarised the effect of SCCPs in mammalian species. Rodent Short-Chain Chlorinated Paraffins: Production, Use and International Regulations 35 studies showed dose-related increases in adenomas and carcinomas in the liver, thyroid and kidney. They concluded that there was insufficient evidence to conclude that the carcinogenicity observations in the liver and thyroid in mice and the benign tumors in the kidney of male rats were a male rat-specific event, and consequently the concern for humans could not be ruled out.

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